Plakophilin 1 anticorps (N-Term)

N° du produit ABIN6938188

Cet anticorps anti-Plakophilin 1 est un anticorps Souris Monoclonal détectant Plakophilin 1 dans WB, IF et FACS. Adapté pour Humain.

Aperçu rapide pour Plakophilin 1 anticorps (N-Term) (ABIN6938188)

Antigène: Plakophilin 1 (PKP1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Plakophilin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 10B2

Détail du produit anti-Plakophilin 1 anticorps

Épitope: N-Term

Specificité: Recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

Réactivité croisée (Details): Human. Mouse.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: N-terminus of human Plakophilin-1 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: U87, HeLa and A431 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Plakophilin 1

Antigène: Plakophilin 1 (PKP1)

Autre désignation: PKP1

Sujet: B6P, Band 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome),Plakophilin-1 (PKP1)
Cellular localisation: Cell Surface and nuclear

Poids moléculaire: 75kDa

ID gène: 5317, 497350

UniProt: Q13835