RPSA/Laminin Receptor anticorps

N° du produit ABIN6938329

Cet anticorps anti-RPSA/Laminin Receptor est un anticorps Souris Monoclonal détectant RPSA/Laminin Receptor dans WB, IF, FACS et IHC (f). Adapté pour Humain.

Aperçu rapide pour RPSA/Laminin Receptor anticorps (ABIN6938329)

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RPSA/Laminin Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: RPSA-2699

Détail du produit anti-RPSA/Laminin Receptor anticorps

Specificité: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-lengthhuman RPSA protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/mL), Immunofluorescence (1-2 μg/mL),Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7, MDA-MB-453or HEK293 cells.Human breast, colon or ovarian carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur RPSA/Laminin Receptor

Antigène: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Autre désignation: RPSA

Sujet: 34/67 kDa Laminin Receptor,37 kDa Laminin Receptor precursor,37/67 kDa Laminin Receptor, 37LRP,40S Ribosomal Protein SA,67 kDa Laminin Receptor, 67LR,Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1,Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA),Laminin Receptor/ RPSA (Marker of Metastatic Potential)
Cellular localisation: Cell Surface,Cytoplasmic and Nuclear

Poids moléculaire: 37-67kDa

ID gène: 3921, 449909

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly