SHBG anticorps

N° du produit ABIN6938381

Détail du produit anti-SHBG anticorps

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SHBG est non-conjugé

Application: ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)

Specificité: Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human SHBG protein

Clone: SHBG-245

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Liver, Placenta or Testis.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur SHBG

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Autre désignation: SHBG (SHBG Produits)

Synonymes: anticorps ABP, anticorps SBP, anticorps TEBG, anticorps Abpa, anticorps shbgl, anticorps wu:fb66h07, anticorps wu:fd55b08, anticorps zgc:123063, anticorps shbg, anticorps sex hormone binding globulin, anticorps sex hormone-binding globulin, anticorps sex hormone binding globulin L homeolog, anticorps SHBG, anticorps Shbg, anticorps shbg, anticorps shbg.L

Sujet: Androgen binding protein (ABP), Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG),Sex Hormone Binding Globulin (SHBG)
Cellular localisation: Cytoplasmic & Extracellular (Secreted)

Poids moléculaire: 45kDa

ID gène: 6462, 632235

UniProt: P04278

Pathways: Hormone Transport