Thrombomodulin anticorps (AA 69-194)
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- Antigène Voir toutes Thrombomodulin (THBD) Anticorps
- Thrombomodulin (THBD)
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Épitope
- AA 69-194
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Thrombomodulin est non-conjugé
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Application
- Western Blotting (WB), ELISA, Coating (Coat), Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)
- Clone
- THBD-1591
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product THBD Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: THP1 cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- Thrombomodulin (THBD)
- Autre désignation
- THBD (THBD Produits)
- Synonymes
- anticorps AHUS6, anticorps BDCA3, anticorps CD141, anticorps THPH12, anticorps THRM, anticorps TM, anticorps AI385582, anticorps THBD, anticorps HAST, anticorps HAST3, anticorps M-PST, anticorps ST1A3/ST1A4, anticorps ST1A5, anticorps STM, anticorps TL-PST, anticorps thrombomodulin, anticorps sulfotransferase family 1A member 3, anticorps THBD, anticorps Thbd, anticorps SULT1A3
- Sujet
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AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM),Thrombomodulin / CD141 (Endothelial Cell Marker)
Cellular localisation: Cell Surface & Cytoplasmic - Poids moléculaire
- ~100kDa
- ID gène
- 7056, 2030
- UniProt
- P07204
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