Uroplakin 3A anticorps (AA 260-279)
Aperçu rapide pour Uroplakin 3A anticorps (AA 260-279) (ABIN6938735)
Antigène
Voir toutes Uroplakin 3A (UPK3A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 260-279
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Specificité
- Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
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Isotype
- IgG
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Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HEK293 cells. Bladder carcinoma.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- Uroplakin 3A (UPK3A)
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Autre désignation
- UPK3A
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Sujet
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UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A,Uroplakin 3A (Bladder Carcinoma Marker)
Cellular localisation: Cell surface -
Poids moléculaire
- 30kDa
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ID gène
- 7380, 632787
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UniProt
- O75631
Antigène
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