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VLDLR anticorps (C-Term)

VLDLR Reactivité: Humain ISt, IHC (f) Hôte: Souris Monoclonal VLDLR-1337 unconjugated
N° du produit ABIN6938760
  • Antigène Voir toutes VLDLR Anticorps
    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
    Épitope
    • 17
    • 16
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 64
    • 25
    • 22
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    Humain
    Hôte
    • 49
    • 15
    Souris
    Clonalité
    • 47
    • 17
    Monoclonal
    Conjugué
    • 23
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp VLDLR est non-conjugé
    Application
    • 55
    • 42
    • 26
    • 24
    • 13
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
    Réactivité croisée (Details)
    Human. Rat.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant human VLDLR fragment from c-terminal
    Clone
    VLDLR-1337
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product VLDLR Anticorps primaire
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
    Autre désignation
    VLDLR (VLDLR Produits)
    Synonymes
    anticorps CARMQ1, anticorps CHRMQ1, anticorps VLDLRCH, anticorps AA408956, anticorps AI451093, anticorps AW047288, anticorps vldlr, anticorps very low density lipoprotein receptor, anticorps very low density lipoprotein receptor S homeolog, anticorps VLDLR, anticorps Vldlr, anticorps vldlr.S
    Sujet
    Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR,VLDL-Receptor (Very Low Density Lipoprotein Receptor)
    Cellular localisation: Cytoplasmic
    Poids moléculaire
    143-161kDa
    ID gène
    7436, 370422
    UniProt
    P98155
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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