VLDLR anticorps (C-Term)
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- Antigène Voir toutes VLDLR Anticorps
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp VLDLR est non-conjugé
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Application
- Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
- Réactivité croisée (Details)
- Human. Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant human VLDLR fragment from c-terminal
- Clone
- VLDLR-1337
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product VLDLR Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- Autre désignation
- VLDLR (VLDLR Produits)
- Synonymes
- anticorps CARMQ1, anticorps CHRMQ1, anticorps VLDLRCH, anticorps AA408956, anticorps AI451093, anticorps AW047288, anticorps vldlr, anticorps very low density lipoprotein receptor, anticorps very low density lipoprotein receptor S homeolog, anticorps VLDLR, anticorps Vldlr, anticorps vldlr.S
- Sujet
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Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR,VLDL-Receptor (Very Low Density Lipoprotein Receptor)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 143-161kDa
- ID gène
- 7436, 370422
- UniProt
- P98155
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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