Recombinant VLDLR anticorps (C-Term)
Aperçu rapide pour Recombinant VLDLR anticorps (C-Term) (ABIN6938761)
Antigène
Voir toutes VLDLR AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- C-Term
-
Specificité
- VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
-
Réactivité croisée (Details)
- Human. Rat.
-
Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
Immunogène
- Recombinant human VLDLR fragment from c-terminal
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Known_Application: ELISA (For coating, order antibody without BSA) Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
Agent conservateur
- Azide free
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
Date de péremption
- 24 months
-
-
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
-
Autre désignation
- VLDLR
-
Sujet
-
Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR,VLDL-Receptor (Very Low Density Lipoprotein Receptor)
Cellular localisation: Cytoplasmic -
Poids moléculaire
- 143-161kDa
-
ID gène
- 7436, 370422
-
UniProt
- P98155
-
Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
-