WT1 anticorps

N° du produit ABIN6938780

Cet anticorps Lapin Polyclonal détecte spécifiquement WT1 dans IHC. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour WT1 anticorps (ABIN6938780)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-WT1 anticorps

Fonction: Wilm’s Tumor 1 (WT1) (Wilm’s Tumor & Mesothelial Marker) Antibody

Specificité: Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.

Purification: 200ug/ml of Ab Purified by Protein A/G.

Immunogène: Recombinant human WT1 protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker)

Sujet:

WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1

K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.

Poids moléculaire: 47-55kDa

ID gène: 7490, 591980

UniProt: P19544

Pathways: Tube Formation