Recombinant YBX1 anticorps
Aperçu rapide pour Recombinant YBX1 anticorps (ABIN6938791)
Antigène
Voir toutes YBX1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker) Antibody
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Specificité
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.
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Réactivité croisée (Details)
- Human.
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Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human full-length YBX1 protein
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Isotype
- IgG1, kappa
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Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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Autre désignation
- YBX1
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Sujet
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BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1
Breast or lung carcinoma., HEK293 or PC12 cells. Prostate, MCF-7, EL4, HeLa, Skeletal muscle.
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Poids moléculaire
- 36kDa
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ID gène
- 4904, 473583
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UniProt
- P67809
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Pathways
- Regulation of Muscle Cell Differentiation
Antigène
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