CGB anticorps

N° du produit ABIN6939105

Cet anticorps Souris Monoclonal détecte spécifiquement CGB dans IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour CGB anticorps (ABIN6939105)

Antigène: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CGB est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: HCGb-211

Détail du produit anti-CGB anticorps

Specificité: This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Réactivité croisée (Details): Human,

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Purified human HCG-beta

Isotype: IgG1

Information d'application

Indications d'application:

Positive Control: Placenta.

Known Application: Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur CGB

Antigène: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Autre désignation: CGB

Sujet: CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB,HCG-beta (Pregnancy & Choriocarcinoma Marker)
Cellular localisation: Cytoplasmic, secreted

Poids moléculaire: 22kDa

ID gène: 1082, 172944

UniProt: P01233