UPK1A anticorps (AA 114-173)

N° du produit ABIN6939114

L’anticorps Souris Monoclonal anti-UPK1A a été validé pour ELISA, Coat et IHC (f). Il convient pour détecter UPK1A dans des échantillons de Humain.

Aperçu rapide pour UPK1A anticorps (AA 114-173) (ABIN6939114)

Antigène: UPK1A (Uroplakin 1a (UPK1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UPK1A est non-conjugé

Application: ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: UPK1A-2921

Détail du produit anti-UPK1A anticorps

Épitope: AA 114-173

Specificité: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

Réactivité croisée (Details): Human,

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein (exact sequence is proprietary)

Isotype: IgG2b

Information d'application

Indications d'application:

Positive Control: Urinary Bladder.

Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur UPK1A

Antigène: UPK1A (Uroplakin 1a (UPK1A))

Autre désignation: UPK1A

Sujet: UP1A, UPIA, UPKA, TSPAN21,Uroplakin 1A (Urothelial Differentiation Marker)
Cellular localisation: Cell Surface

Poids moléculaire: 29kDa

ID gène: 11045, 159309

UniProt: O00322