GPN1 anticorps

N° du produit ABIN6939142

L’anticorps Souris Monoclonal anti-GPN1 a été validé pour WB, ELISA et Coat. Il convient pour détecter GPN1 dans des échantillons de Humain.

Aperçu rapide pour GPN1 anticorps (ABIN6939142)

Antigène: GPN1 (GPN-Loop GTPase 1 (GPN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: GPN1-2350

Détail du produit anti-GPN1 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human GPN1 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Pancreas, Testis, Thyroid or Bladder.

Known Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GPN1

Antigène: GPN1 (GPN-Loop GTPase 1 (GPN1))

Autre désignation: GPN1

Sujet: GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.

Poids moléculaire: 42kDa

ID gène: 11321