CLTA/CLTB anticorps (N-Term)

N° du produit ABIN6939150

Cet anticorps Souris Monoclonal détecte spécifiquement CLTA/CLTB dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CLTA/CLTB anticorps (N-Term) (ABIN6939150)

Antigène: CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLTA/CLTB est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CLC-1421

Détail du produit anti-CLTA/CLTB anticorps

Épitope: N-Term

Fonction: Clathrin, Light Chain Antibody

Specificité: Recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Purified recombinant N-terminal fragment of human Clathrin Light Chain

Isotype: IgG2b, kappa

Information d'application

Indications d'application:

Positive Control: HeLa cells. Placenta or Prostate Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CLTA/CLTB

Antigène: CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))

Autre désignation: CLTA and CLTB

Sujet:

Clathrin light chain A, Clathrin light chain B, Clathrin light chain LCA, Clathrin light chain LCB, Clathrin light polypeptide A, Clathrin light polypeptide B, Clathrin, light polypeptide (Lca), Clathrin, light polypeptide (Lcb), CLTA, CLTB

HeLa cells. Placenta or Prostate Carcinoma.

Poids moléculaire: 31-44kDa

ID gène: 1211, 1212, 484241

UniProt: P09496, P09497