Elastin anticorps

N° du produit ABIN6939301

Détail du produit anti-Elastin anticorps

Antigène: Elastin (ELN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Elastin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human Elastin protein

Clone: ELN-1981

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Elastin

Antigène: Elastin (ELN)

Autre désignation: ELN (ELN Produits)

Synonymes: anticorps SVAS, anticorps WBS, anticorps WS, anticorps AI385707, anticorps AI480567, anticorps E030024M20Rik, anticorps RATTREL11, anticorps TREL11, anticorps Trela, anticorps Trela26, anticorps ELN, anticorps elastin, anticorps ELN, anticorps Eln, anticorps LOC574132, anticorps Tcur_2481, anticorps Kfla_2289, anticorps LOC100620140

Sujet: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Poids moléculaire: 70kDa

ID gène: 2006

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization