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Estrogen Receptor alpha anticorps (AA 129-312)

ESR1 Reactivité: Humain IHC, FACS, StM Hôte: Souris Monoclonal ESR1-3559 unconjugated
N° du produit ABIN6939347
  • Antigène Voir toutes Estrogen Receptor alpha (ESR1) Anticorps
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Épitope
    • 32
    • 30
    • 26
    • 23
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    • 21
    • 21
    • 16
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    • 16
    • 16
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 129-312
    Reactivité
    • 481
    • 173
    • 167
    • 19
    • 18
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 393
    • 96
    • 2
    • 1
    Souris
    Clonalité
    • 372
    • 122
    Monoclonal
    Conjugué
    • 223
    • 35
    • 24
    • 22
    • 19
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Estrogen Receptor alpha est non-conjugé
    Application
    • 378
    • 172
    • 141
    • 119
    • 97
    • 94
    • 80
    • 67
    • 40
    • 38
    • 24
    • 15
    • 10
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)
    Specificité
    This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human ESR1 protein fragment (around aa129-312) (exact sequence is proprietary)
    Clone
    ESR1-3559
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ESR1 Anticorps primaire
  • Indications d'application

    Positive Control: MCF-7 cells. Breast or Endometrial Carcinoma (IHC).

    Known Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Autre désignation
    ESR1 (ESR1 Produits)
    Synonymes
    anticorps LOC398734, anticorps AA420328, anticorps AU041214, anticorps ER-alpha, anticorps ER[a], anticorps ERa, anticorps ERalpha, anticorps ESR, anticorps Estr, anticorps Estra, anticorps Nr3a1, anticorps NR3A1, anticorps eralpha, anticorps zfER[a], anticorps ER, anticorps ESRA, anticorps ESTRR, anticorps Era, anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps Esr, anticorps RNESTROR, anticorps ERALPHA, anticorps er, anticorps esr, anticorps nr3a1, anticorps XER, anticorps era, anticorps esra, anticorps ERbeta, anticorps xesr-1, anticorps xlERalpha1, anticorps xlERalpha2, anticorps ESR1, anticorps estrogen receptor 1 L homeolog, anticorps estrogen receptor 1 (alpha), anticorps estrogen receptor 1, anticorps A kinase (PRKA) anchor protein 12b, anticorps esr1.L, anticorps Esr1, anticorps ESR1, anticorps esr1, anticorps akap12b
    Poids moléculaire
    ~67kDa
    ID gène
    2099
    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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