Recombinant MLANA anticorps

N° du produit ABIN6939389

Cet anticorps Souris Monoclonal détecte spécifiquement MLANA dans IHC, ISt et StM. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour Recombinant MLANA anticorps (ABIN6939389)

Antigène: MLANA (Melan A (MLANA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MLANA est non-conjugé

Application: Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)

Clone: RMLANA-788

Détail du produit anti-MLANA anticorps

Specificité: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length hMART-1 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: SK-MEL-13 and SK-MEL-19 melanoma cell lines. Human melanoma tissues.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MLANA

Antigène: MLANA (Melan A (MLANA))

Autre désignation: MLANA

Poids moléculaire: 20-22kDa (doublet)

ID gène: 2315

UniProt: Q16655