ALPL anticorps

N° du produit ABIN6939448

Cet anticorps Souris Monoclonal détecte spécifiquement ALPL dans IHC et StM. Il présente une réactivité envers Humain et Boeuf (Vache).

Aperçu rapide pour ALPL anticorps (ABIN6939448)

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reactivité: Humain, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ALPL est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: ALPL-597

Détail du produit anti-ALPL anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant human ALPL protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Intestine.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur ALPL

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Autre désignation: ALPL

Sujet: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.

Poids moléculaire: 55kDa

ID gène: 249

UniProt: P05186