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PLAP anticorps

ALPP Reactivité: Humain IHC, ISt Hôte: Souris Monoclonal ALP-870 unconjugated
N° du produit ABIN6939451
  • Antigène Voir toutes PLAP (ALPP) Anticorps
    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
    Reactivité
    • 128
    • 22
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 75
    • 53
    • 2
    Souris
    Clonalité
    • 68
    • 61
    Monoclonal
    Conjugué
    • 70
    • 11
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLAP est non-conjugé
    Application
    • 94
    • 53
    • 53
    • 36
    • 23
    • 19
    • 14
    • 13
    • 12
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunostaining (ISt)
    Specificité
    Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human ALPP protein
    Clone
    ALP-870
    Isotype
    IgG
    Top Product
    Discover our top product ALPP Anticorps primaire
  • Indications d'application

    Positive Control: HepG2 cells. Placenta or seminoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(No special pretreatment is required for the immunohistochemical staining of formalin-fixed tissues.)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
    Autre désignation
    ALPP (ALPP Produits)
    Synonymes
    anticorps ECK0378, anticorps JW0374, anticorps psiA, anticorps ALP, anticorps PALP, anticorps PLAP, anticorps PLAP-1, anticorps ILC, anticorps CTACK, anticorps ESkine, anticorps Akp2, anticorps alp, anticorps zgc:56672, anticorps DDBDRAFT_0205491, anticorps DDBDRAFT_0231570, anticorps DDB_0205491, anticorps DDB_0231570, anticorps ALPI, anticorps Actn2lp, anticorps Alp, anticorps bacterial alkaline phosphatase, anticorps alkaline phosphatase, placental, anticorps alkaline phosphatase, placental type, anticorps C-C motif chemokine ligand 27, anticorps alkaline phosphatase, liver/bone/kidney, anticorps alkaline phosphatase, anticorps alkaline phosphatase, intestinal, anticorps PDZ and LIM domain 3, anticorps phoA, anticorps ALPP, anticorps LOC100436725, anticorps CCL27, anticorps alpl, anticorps alp, anticorps ALPI, anticorps Pdlim3, anticorps Alpp
    Poids moléculaire
    70kDa
    ID gène
    250
    UniProt
    P05187
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