FUT3 anticorps

N° du produit ABIN6939469

Cet anticorps Souris Monoclonal détecte spécifiquement FUT3 dans IHC, IF, StM et ISt. Il présente une réactivité envers Humain et Cobaye.

Aperçu rapide pour FUT3 anticorps (ABIN6939469)

Antigène: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Reactivité: Humain, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FUT3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM), Immunostaining (ISt)

Clone: 2-25LE-same as LWB01

Détail du produit anti-FUT3 anticorps

Purification: Purified by Protein A/G

Immunogène: Mucin isolated from a human ovarian cyst fluid

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Colon.

Known Application: Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur FUT3

Antigène: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Autre désignation: FUT3

Sujet: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.

Poids moléculaire: 45kDa

ID gène: 2525

UniProt: P21217