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SERBP1 anticorps (AA 3-139)

SERBP1 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal SERBP1-3496 unconjugated
N° du produit ABIN6939489
  • Antigène Voir toutes SERBP1 Anticorps
    SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
    Épitope
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-139
    Reactivité
    • 46
    • 27
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 14
    Souris
    Clonalité
    • 34
    • 12
    Monoclonal
    Conjugué
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SERBP1 est non-conjugé
    Application
    • 25
    • 13
    • 13
    • 13
    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
    Clone
    SERBP1-3496
    Isotype
    IgG2c kappa
    Top Product
    Discover our top product SERBP1 Anticorps primaire
  • Indications d'application

    Positive Control: Human kidney or bladder tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
    Autre désignation
    SERBP1 (SERBP1 Produits)
    Synonymes
    anticorps CHD3IP, anticorps HABP4L, anticorps PAI-RBP1, anticorps PAIRBP1, anticorps 1200009K13Rik, anticorps 9330147J08Rik, anticorps AL022786, anticorps Pairbp1, anticorps Pai-Rbp1, anticorps Rda288, anticorps cgi-55, anticorps chd3ip, anticorps habp4l, anticorps pai-rbp1, anticorps pairbp1, anticorps rda288, anticorps hm:zeh0245, anticorps serbp1, anticorps wu:fa12d05, anticorps wu:fb36e07, anticorps wu:fc16f12, anticorps wu:fj13e12, anticorps zgc:55489, anticorps SERPINE1 mRNA binding protein 1, anticorps serpine1 mRNA binding protein 1, anticorps Serpine1 mRNA binding protein 1, anticorps SERPINE1 mRNA binding protein 1 L homeolog, anticorps SERPINE1 mRNA binding protein 1a, anticorps SERBP1, anticorps Serbp1, anticorps serbp1.L, anticorps serbp1a
    Sujet
    PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein), also known as SERBP1 (SERPINE1 mRNA-binding protein 1), CGI-55, CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein), HABP4L or PAI-RBP1, is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterone s antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer, suggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis.
    Poids moléculaire
    60kDa
    ID gène
    26135
    UniProt
    Q8NC51
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