NKX2-8 anticorps (AA 10-123)

N° du produit ABIN6939492

Détail du produit anti-NKX2-8 anticorps

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Épitope: AA 10-123

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Purified by Protein A/G

Immunogène: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Clone: NKX28-2547

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).

Known Application: Western Blot (0.5 μg-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX2-8 (NKX2-8 Produits)

Synonymes: anticorps NKX2.8, anticorps NKX2H, anticorps Nkx2-9, anticorps Nkx-2.9, anticorps Nkx2-8, anticorps Nkx2.9, anticorps tinman, anticorps NK2 homeobox 8, anticorps NK2 homeobox 9, anticorps NKX2-8, anticorps Nkx2-9, anticorps Nkx2-8

Sujet: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Poids moléculaire: 26kDa

ID gène: 26257

UniProt: O15522