AMPD3 anticorps

N° du produit ABIN6939530

Cet anticorps Souris Monoclonal détecte spécifiquement AMPD3 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour AMPD3 anticorps (ABIN6939530)

Antigène: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMPD3 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AMPD3-901

Détail du produit anti-AMPD3 anticorps

Fonction: AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody

Specificité: It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human AMDP3 protein

Isotype: IgG2b, kappa

Information d'application

Indications d'application:

Positive Control: RBC. Fetal liver, Spleen or Placenta.

Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur AMPD3

Antigène: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Autre désignation: AMPD3

Sujet:

Adenosine monophosphate deaminase (isoform E), AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, Ampd3, Erythrocyte AMP deaminase, Erythrocyte specific AMP deaminase, Erythrocyte specific protein, Erythrocyte type AMP deaminase, Myoadenylate deaminase

RBC. Fetal liver, Spleen or Placenta.

Poids moléculaire: ~90kDa

ID gène: 272, 501890

UniProt: Q01432