GP2 anticorps (AA 35-179)

N° du produit ABIN6939543

Cet anticorps Souris Monoclonal détecte spécifiquement GP2 dans IHC, ELISA, Coat et StM. Il présente une réactivité envers Humain.

Aperçu rapide pour GP2 anticorps (AA 35-179) (ABIN6939543)

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GP2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Clone: GP2-1803

Détail du produit anti-GP2 anticorps

Épitope: AA 35-179

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: PANC-1 cells. Pancreas.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GP2

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Autre désignation: GP2

Sujet: GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

Poids moléculaire: 59kDa

ID gène: 2813

UniProt: P55259