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TNC anticorps

TNC Reactivité: Humain IHC, IF, FACS, StM Hôte: Souris Monoclonal SPM319 unconjugated
N° du produit ABIN6939675
  • Antigène Voir toutes TNC Anticorps
    TNC (Tenascin C (TNC))
    Reactivité
    • 78
    • 43
    • 37
    • 15
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 70
    • 30
    • 2
    • 2
    • 1
    Souris
    Clonalité
    • 64
    • 41
    Monoclonal
    Conjugué
    • 47
    • 11
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNC est non-conjugé
    Application
    • 73
    • 26
    • 26
    • 25
    • 23
    • 17
    • 13
    • 11
    • 11
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Specificité
    In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
    Aucune reactivité croisée
    Rat (Rattus)
    Purification
    Purified by Protein A/G
    Immunogène
    Human breast carcinoma
    Clone
    SPM319
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TNC Anticorps primaire
  • Indications d'application

    Positive Control: Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell and lung carcinomas. Staining of normal fibroblasts serves as internal positive control.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    TNC (Tenascin C (TNC))
    Autre désignation
    TNC (TNC Produits)
    Synonymes
    anticorps tn, anticorps 150-225, anticorps GMEM, anticorps GP, anticorps HXB, anticorps JI, anticorps TN, anticorps TN-C, anticorps AI528729, anticorps C130033P17Rik, anticorps Hxb, anticorps Ten, anticorps cytotactin, anticorps tenascin-C, anticorps P230, anticorps tenc, anticorps wu:fk04d02, anticorps tenascin C L homeolog, anticorps tenascin C, anticorps tnc.L, anticorps TNC, anticorps MCYG_00667, anticorps tnc, anticorps Tnc
    Poids moléculaire
    210kDa and 300kDa
    ID gène
    3371
    UniProt
    P24821
    Pathways
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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