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Liver Arginase anticorps (AA 11-97)

Cet anticorps Souris Monoclonal détecte spécifiquement Liver Arginase dans WB, IHC et StM. Il présente une réactivité envers Humain.
N° du produit ABIN6939857

Aperçu rapide pour Liver Arginase anticorps (AA 11-97) (ABIN6939857)

Antigène

Voir toutes Liver Arginase (ARG1) Anticorps
Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité

  • 126
  • 63
  • 47
  • 12
  • 10
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 113
  • 41
  • 5
  • 3
  • 2
Souris

Clonalité

  • 107
  • 56
  • 1
Monoclonal

Conjugué

  • 98
  • 11
  • 11
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Liver Arginase est non-conjugé

Application

  • 110
  • 58
  • 51
  • 31
  • 23
  • 21
  • 15
  • 14
  • 13
  • 11
  • 10
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Clone

ARG1-1125
  • Épitope

    • 24
    • 16
    • 12
    • 11
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-97

    Specificité

    Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

    Purification

    Purified by Protein A/G

    Immunogène

    Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)

    Isotype

    IgG3 kappa
  • Indications d'application

    Positive Control: 293T cells. Hepatocellular Carcinoma (HCC).

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-80 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Date de péremption

    24 months
  • Antigène

    Liver Arginase (ARG1) (Arginase, Liver (ARG1))

    Autre désignation

    ARG1

    Poids moléculaire

    35-38kDa

    ID gène

    383

    UniProt

    P05089

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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