Cytokeratin 5 anticorps (AA 316-590)

N° du produit ABIN6939864

Détail du produit anti-Cytokeratin 5 anticorps

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Épitope: AA 316-590

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 5 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificité: This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa 316-590) of human Cytokeratin 5 (KRT5) protein (exact sequence is proprietary)

Clone: KRT5-3594

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: MCF-7 or HeLa cells. Human tonsil, esophagus or bladder tissue (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cytokeratin 5

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Autre désignation: KRT5 (KRT5 Produits)

Synonymes: anticorps 3300001P10Rik, anticorps AW146334, anticorps CK5, anticorps K5, anticorps Krt2-5, anticorps Tfip8, anticorps DDD, anticorps DDD1, anticorps EBS2, anticorps KRT5A, anticorps Sak57, anticorps ckii, anticorps wu:fb02h09, anticorps wu:fj02d02, anticorps wu:fk78b12, anticorps zfCKII, anticorps KRT75, anticorps CK-5, anticorps Keratin-5, anticorps keratin 5, anticorps Krt5, anticorps KRT5, anticorps krt5

Poids moléculaire: 58kDa

ID gène: 3852

UniProt: P13647