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Recombinant Keratin 10 anticorps

KRT10 Reactivité: Humain, Souris IHC, StM Hôte: Lapin Monoclonal KRT10-1990R unconjugated Recombinant Antibody
N° du produit ABIN6939903
  • Antigène Voir toutes Keratin 10 (KRT10) Anticorps
    Keratin 10 (KRT10)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 120
    • 56
    • 50
    • 27
    • 18
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 74
    • 49
    • 2
    Lapin
    Clonalité
    • 67
    • 58
    Monoclonal
    Conjugué
    • 71
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Keratin 10 est non-conjugé
    Application
    • 80
    • 55
    • 53
    • 39
    • 34
    • 27
    • 15
    • 14
    • 13
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human full-length KRT10 protein
    Clone
    KRT10-1990R
    Isotype
    IgG
    Top Product
    Discover our top product KRT10 Anticorps primaire
  • Indications d'application

    Positive Control: A431, HeLa, MCF7 cells. Esophagus or tonsil.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Keratin 10 (KRT10)
    Autre désignation
    KRT10 (KRT10 Produits)
    Synonymes
    anticorps BCIE, anticorps BIE, anticorps CK10, anticorps EHK, anticorps K10, anticorps KPP, anticorps D130054E02Rik, anticorps K1C1, anticorps Krt-1.10, anticorps Krt1-10, anticorps Ka10, anticorps Ker10, anticorps KRT10, anticorps KRT25, anticorps KRT27, anticorps KRT28, anticorps keratin 10, anticorps keratin 10, type I S homeolog, anticorps keratin, type I cytoskeletal 25, anticorps KRT10, anticorps Krt10, anticorps krt10.S, anticorps LOC101085587
    Poids moléculaire
    56.5kDa
    ID gène
    3858
    UniProt
    P13645
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