RPSA/Laminin Receptor anticorps
Aperçu rapide pour RPSA/Laminin Receptor anticorps (ABIN6939957)
Antigène
Voir toutes RPSA/Laminin Receptor (RPSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified by Protein A/G
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Immunogène
- Recombinant full-length human RPSA protein
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Isotype
- IgG1 kappa
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Indications d'application
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Positive Control: MCF-7, MDA-MB-453, SK-BR3, THP1, HL60, HeLa or HEK293 cells. Breast, Colon or Ovarian Carcinoma, Tonsil.
Known Application: Flow Cytometry (1-2 μg/mL), Immunofluorescence (1-2 μg/mL),Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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Autre désignation
- RPSA
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Sujet
- Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
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Poids moléculaire
- 37-67kDa
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ID gène
- 3921
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UniProt
- P08865
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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