LMO2 anticorps (AA 23-140)

N° du produit ABIN6939966

Cet anticorps Souris Monoclonal détecte spécifiquement LMO2 dans WB et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LMO2 anticorps (AA 23-140) (ABIN6939966)

Antigène: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LMO2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: LMO2-1971

Détail du produit anti-LMO2 anticorps

Épitope: AA 23-140

Fonction: LMO2 (B-Cell Marker) Antibody

Specificité: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application:

Positive Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.

Known Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur LMO2

Antigène: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Autre désignation: LMO2

Sujet:

Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2

K562 or Hodgkin s lymphoma, Ramos or Raji cells. Human placenta, pancreas and Brain

Poids moléculaire: 24kDa

ID gène: 4005, 34560

UniProt: P25791

Pathways: Chromatin Binding