MUC1 anticorps
Aperçu rapide pour MUC1 anticorps (ABIN6940099)
Antigène
Voir toutes MUC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
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Purification
- Purified by Protein A/G
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Immunogène
- Human milk-fat globule membranes (HMFGM)
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Isotype
- IgG2a kappa
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Indications d'application
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Positive Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- MUC1 (Mucin 1 (MUC1))
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Autre désignation
- MUC1
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Poids moléculaire
- 265-400kDa
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ID gène
- 4582
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UniProt
- P15941
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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