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MUC4 anticorps (AA 1730-1864)

MUC4 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal MUC4-3084 unconjugated
N° du produit ABIN6940125
  • Antigène Voir toutes MUC4 Anticorps
    MUC4 (Mucin 4, Cell Surface Associated (MUC4))
    Épitope
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1730-1864
    Reactivité
    • 39
    • 13
    • 3
    Humain
    Hôte
    • 32
    • 8
    Souris
    Clonalité
    • 23
    • 17
    Monoclonal
    Conjugué
    • 24
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MUC4 est non-conjugé
    Application
    • 22
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment (around aa 1730-1864) of human MUC4 protein (exact sequence is proprietary)
    Clone
    MUC4-3084
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MUC4 Anticorps primaire
  • Indications d'application

    Positive Control: Stomach, Colon or esophagus.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    MUC4 (Mucin 4, Cell Surface Associated (MUC4))
    Autre désignation
    MUC4 (MUC4 Produits)
    Synonymes
    anticorps 4933405I11Rik, anticorps Asgp, anticorps ASGP, anticorps HSA276359, anticorps MUC-4, anticorps ASGP-1, anticorps Psmc, anticorps mucin 4, anticorps mucin 4, cell surface associated, anticorps Muc4, anticorps MUC4
    Sujet
    The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
    Poids moléculaire
    235kDa
    ID gène
    4585
    UniProt
    Q99102
    Pathways
    Regulation of Leukocyte Mediated Immunity
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