MUC6 anticorps

N° du produit ABIN6940141

Cet anticorps anti-MUC6 est un anticorps Souris Monoclonal détectant MUC6 dans IHC et StM. Adapté pour Humain.

Aperçu rapide pour MUC6 anticorps (ABIN6940141)

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC6 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: MUC6-916

Détail du produit anti-MUC6 anticorps

Aucune reactivité croisée: Rat (Rattus)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Human stomach tissue (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC6

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Autre désignation: MUC6

Sujet: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Poids moléculaire: 252kDa

ID gène: 4588

UniProt: Q6W4X9