Recombinant NEFL anticorps

N° du produit ABIN6940190

Cet anticorps Lapin Monoclonal détecte spécifiquement NEFL dans IHC et StM. Il présente une réactivité envers Humain, Rat, Porc, Boeuf (Vache) et Poulet.

Aperçu rapide pour Recombinant NEFL anticorps (ABIN6940190)

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Porc, Boeuf (Vache), Poulet

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NEFL est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: NEFL-2983R

Détail du produit anti-NEFL anticorps

Specificité: This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human NEFL protein

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: Brain, Neuroblastoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NEFL

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Autre désignation: NEFL

Poids moléculaire: 68kDa

ID gène: 4747

UniProt: P07196