PAX5 anticorps (AA 235-382)

N° du produit ABIN6940256

Cet anticorps anti-PAX5 est un anticorps Souris Monoclonal détectant PAX5 dans IHC et StM. Adapté pour Humain.

Aperçu rapide pour PAX5 anticorps (AA 235-382) (ABIN6940256)

Antigène: PAX5 (Paired Box 5 (PAX5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX5 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: PAX5-3735

Détail du produit anti-PAX5 anticorps

Épitope: AA 235-382

Purification: Purified by Protein A/G

Immunogène: A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Daudi or Ramos cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PAX5

Antigène: PAX5 (Paired Box 5 (PAX5))

Autre désignation: PAX5

Sujet: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 21,000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.

Poids moléculaire: 42kDa

ID gène: 5079

UniProt: Q02548