PAX7 anticorps (AA 301-505)

N° du produit ABIN6940261

Cet anticorps anti-PAX7 Monoclonal Souris (Clone SPM613) (ABIN6940261) détecte spécifiquement PAX7 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PAX7 anticorps (AA 301-505) (ABIN6940261)

Antigène: PAX7 (Paired Box 7 (PAX7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX7 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: SPM613

Détail du produit anti-PAX7 anticorps

Épitope: AA 301-505

Fonction: PAX7 (Rhabdomyosarcoma Marker) Antibody

Specificité: The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Positive Control: Rhabdomyosarcoma (RMS) or Testicular Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris Buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PAX7

Antigène: PAX7 (Paired Box 7 (PAX7))

Autre désignation: PAX7

Sujet:

HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2

Rhabdomyosarcoma (RMS) or Testicular Carcinoma.

Poids moléculaire: 57kDa

ID gène: 5081, 113253

UniProt: P23759