Plakophilin 1 anticorps (N-Term)
Aperçu rapide pour Plakophilin 1 anticorps (N-Term) (ABIN6940317)
Antigène
Voir toutes Plakophilin 1 (PKP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- N-Term
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Specificité
- Recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.
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Purification
- Purified by Protein A/G
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Immunogène
- N-terminus of human Plakophilin-1 protein
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Isotype
- IgG1 kappa
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Indications d'application
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Positive Control: U87, HeLa and A431 cells.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Plakophilin 1 (PKP1)
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Autre désignation
- PKP1
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Poids moléculaire
- 75kDa
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ID gène
- 5317
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UniProt
- Q13835
Antigène
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