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Plakophilin 1 anticorps (N-Term)

L’anticorps Souris Monoclonal anti-Plakophilin 1 a été validé pour WB, IF et FACS. Il convient pour détecter Plakophilin 1 dans des échantillons de Humain et Souris.
N° du produit ABIN6940317

Aperçu rapide pour Plakophilin 1 anticorps (N-Term) (ABIN6940317)

Antigène

Voir toutes Plakophilin 1 (PKP1) Anticorps
Plakophilin 1 (PKP1)

Reactivité

  • 21
  • 14
  • 1
Humain, Souris

Hôte

  • 17
  • 6
  • 1
Souris

Clonalité

  • 16
  • 8
Monoclonal

Conjugué

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Plakophilin 1 est non-conjugé

Application

  • 24
  • 12
  • 9
  • 8
  • 7
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone

10B2
  • Épitope

    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    Specificité

    Recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

    Purification

    Purified by Protein A/G

    Immunogène

    N-terminus of human Plakophilin-1 protein

    Isotype

    IgG1 kappa
  • Indications d'application

    Positive Control: U87, HeLa and A431 cells.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-80 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Date de péremption

    24 months
  • Antigène

    Plakophilin 1 (PKP1)

    Autre désignation

    PKP1

    Poids moléculaire

    75kDa

    ID gène

    5317

    UniProt

    Q13835
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