ENAH anticorps (AA 485-589)

N° du produit ABIN6940390

Détail du produit anti-ENAH anticorps

Antigène: ENAH (Enabled Homolog (ENAH))

Épitope: AA 485-589

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ENAH est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)

Clone: ENAH-1988

Isotype: IgG2c kappa

Information d'application

Indications d'application:

Positive Control: MCF-7 cells. Uterus.

Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur ENAH

Antigène: ENAH (Enabled Homolog (ENAH))

Autre désignation: ENAH (ENAH Produits)

Synonymes: anticorps ENA, anticorps MENA, anticorps NDPP1, anticorps AI464316, anticorps AW045240, anticorps Mena, anticorps Ndpp1, anticorps WBP8, anticorps id:ibd2798, anticorps si:ch211-215p14.1, anticorps zgc:103638, anticorps ENAH, actin regulator, anticorps enabled homolog (Drosophila), anticorps Enah, anticorps ENAH, anticorps enah

Sujet: The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.

Poids moléculaire: 80/88/140kDa

ID gène: 55740

UniProt: Q8N8S7