PMEPA1 anticorps

N° du produit ABIN6940418

L’anticorps anti-PMEPA1 Monoclonal Souris est utilisé pour la détection de PMEPA1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour PMEPA1 anticorps (ABIN6940418)

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PMEPA1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PMEPA1-2697

Détail du produit anti-PMEPA1 anticorps

Fonction: PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Antibody

Specificité: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human PMEPA1 protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Positive Control: SKBR-3 cells. Prostate, Breast or Renal Cell Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PMEPA1

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Autre désignation: PMEPA1

Sujet:

PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

Human prostate, breast or renal cell carcinoma tissue (IHC). SKBR-3 cells.

Poids moléculaire: 32kDa

ID gène: 56937, 517155

UniProt: Q969W9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway