RBP4 anticorps

N° du produit ABIN6940483

Cet anticorps anti-RBP4 est un anticorps Souris Monoclonal détectant RBP4 dans WB, IHC, IF et StM. Adapté pour Humain, Souris, Rat, Lapin, Singe et Chévre.

Aperçu rapide pour RBP4 anticorps (ABIN6940483)

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reactivité: Humain, Souris, Rat, Lapin, Singe, Chévre

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RBP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

Clone: SPM442

Détail du produit anti-RBP4 anticorps

Specificité: Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This MAb recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Purification: Purified by Protein A/G

Immunogène: Retinol binding protein Purified from human plasma

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Liver or placenta.

Known Application: Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur RBP4

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Autre désignation: RBP

Poids moléculaire: 21-25kDa

ID gène: 5947, 5948, 5950

UniProt: P02753, P09455, P50120

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response