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Fascin anticorps

FSCN1 Reactivité: Humain, Rat WB, IHC, FACS, IF, StM Hôte: Souris Monoclonal FSCN1-418 unconjugated
N° du produit ABIN6940609
  • Antigène Voir toutes Fascin (FSCN1) Anticorps
    Fascin (FSCN1)
    Reactivité
    • 90
    • 52
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 77
    • 35
    • 1
    • 1
    Souris
    Clonalité
    • 68
    • 46
    Monoclonal
    Conjugué
    • 47
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Fascin est non-conjugé
    Application
    • 80
    • 46
    • 37
    • 31
    • 28
    • 28
    • 20
    • 14
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
    Specificité
    Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
    Purification
    Purified by Protein A/G
    Immunogène
    Full length recombinant human FSCN1 protein
    Clone
    FSCN1-418
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product FSCN1 Anticorps primaire
  • Indications d'application

    Positive Control: K562, HeLa, MCF-7, PC-3 or BEWO cells. Hodgkin's lymphoma, Ovarian or Testicular Carcinoma.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Fascin (FSCN1)
    Autre désignation
    FSCN1 (FSCN1 Produits)
    Synonymes
    anticorps CG15331, anticorps CG1536, anticorps CG32858, anticorps Dmel\\CG32858, anticorps SN, anticorps Sn, anticorps fs(1)A1057, anticorps fs(1)K1421, anticorps fs(1)K418, anticorps fs(1)K473, anticorps fs(1)K743, anticorps fs(1)M45, anticorps p55, anticorps snl, anticorps MGC75811, anticorps fscn1, anticorps sb:cb589, anticorps zgc:153632, anticorps AI663989, anticorps Fan1, anticorps fascin-1, anticorps Fascin, anticorps fscn, anticorps FAN1, anticorps HSN, anticorps SNL, anticorps fascin, anticorps singed, anticorps fascin actin-bundling protein 1, anticorps fascin actin-bundling protein 1a, anticorps fascin actin-bundling protein 1 L homeolog, anticorps sn, anticorps fscn1, anticorps fscn1a, anticorps Fscn1, anticorps fscn1.L, anticorps FSCN1
    Poids moléculaire
    55kDa
    ID gène
    6624
    UniProt
    Q16658
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