SULT1E1 anticorps

N° du produit ABIN6940673

Cet anticorps Souris Monoclonal détecte spécifiquement SULT1E1 dans IHC et StM. Il présente une réactivité envers Humain.

Aperçu rapide pour SULT1E1 anticorps (ABIN6940673)

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SULT1E1 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: CPTC-SULT1E1-1

Détail du produit anti-SULT1E1 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human SULT1E1 protein

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: HEP G2, liver, intestine and kidney.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur SULT1E1

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Autre désignation: SULT1E1

Sujet: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

Poids moléculaire: 35kDa

ID gène: 6783

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis