Transferrin anticorps (AA 311-445)
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- Antigène Voir toutes Transferrin (TF) Anticorps
- Transferrin (TF)
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Épitope
- AA 311-445
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Transferrin est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment (around aa 311-445) of human TF protein (exact sequence is proprietary)
- Clone
- TF-3001
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TF Anticorps primaire
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- Indications d'application
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Positive Control: Jurkat, HeLa, MCF-7 or K562 cells. Human liver.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- Transferrin (TF)
- Autre désignation
- Transferrin (Early Marker of Oligodendrocytes) (TF Produits)
- Synonymes
- anticorps ltf, anticorps pro1557, anticorps pro2086, anticorps mgc107777, anticorps LOC692564, anticorps TF, anticorps LOC100144362, anticorps tf, anticorps LTF, anticorps TFEW, anticorps conalbumin, anticorps tf-b, anticorps MGC64306, anticorps PRO1557, anticorps PRO2086, anticorps TFQTL1, anticorps AI266983, anticorps Cd176, anticorps HP, anticorps Tf, anticorps Tfn, anticorps hpx, anticorps Trf, anticorps cb285, anticorps gavi, anticorps id:ibd3238, anticorps id:ibd3525, anticorps sb:cb285, anticorps wu:fb57g06, anticorps wu:fb62h02, anticorps wu:fb63h10, anticorps wu:fb64h10, anticorps zgc:112154, anticorps 143958_at, anticorps CG6186, anticorps Dmel\\CG6186, anticorps TSF1, anticorps anon-EST:Posey265, anticorps tsf1, anticorps Pro-TRH, anticorps IL-5, anticorps STF I, anticorps TRF1, anticorps sTF1, anticorps sTf, anticorps tf1, anticorps transferrin, anticorps serotransferrin, anticorps transferrin (ovotransferrin), anticorps transferrin L homeolog, anticorps melanotransferrin, anticorps transferrin-a, anticorps Transferrin 1, anticorps thyrotropin releasing hormone, anticorps interleukin 5, anticorps TF, anticorps LOC477072, anticorps tf, anticorps Tf, anticorps LOC100144362, anticorps tf.L, anticorps LOC5575625, anticorps Trf, anticorps tfa, anticorps Tsf1, anticorps TRH, anticorps IL5, anticorps LOC101085148, anticorps LOC100726872, anticorps trf
- Sujet
- Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which contain an Fe-binding site. The majority of transferrin is synthesized in the liver and secreted into the blood, but it is also produced in lower amounts in testis and brain as well as in oligodendrocytes, where transferrin is an early marker of oligodendrocyte differentiation. From the blood, transferrin is internalized by erythroblasts and reticulocytes upon binding the transferrin receptor (TfR), also designated CD71, through a system of coated pits and vesicles. After Fe release, transferrin is returned to the extracellular medium, where it can be reused. Defects in the transferrin gene results in atransferrinemia, a rare autosomal recessive disorder characterized by microcytic anemia and iron loading.
- Poids moléculaire
- 79kDa
- ID gène
- 7018
- UniProt
- P02787
- Pathways
- Transition Metal Ion Homeostasis
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