Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Recombinant NKX2-1 anticorps

NKX2-1 Reactivité: Humain, Souris, Rat IHC, StM Hôte: Lapin Monoclonal NX2-1-1855R unconjugated Recombinant Antibody
N° du produit ABIN6940746
  • Antigène Voir toutes NKX2-1 Anticorps
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 81
    • 36
    • 36
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 53
    • 29
    Lapin
    Clonalité
    • 42
    • 40
    Monoclonal
    Conjugué
    • 41
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NKX2-1 est non-conjugé
    Application
    • 45
    • 37
    • 30
    • 27
    • 20
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human full-length TTF-1 protein
    Clone
    NX2-1-1855R
    Isotype
    IgG
    Top Product
    Discover our top product NKX2-1 Anticorps primaire
  • Indications d'application

    Positive Control: MAD109, MLE-15, H441-4 or H345 cells. Normal thyroid or lung.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Autre désignation
    NKX2-1 (NKX2-1 Produits)
    Synonymes
    anticorps BCH, anticorps BHC, anticorps NK-2, anticorps NKX2.1, anticorps NKX2A, anticorps TEBP, anticorps TITF1, anticorps TTF-1, anticorps TTF1, anticorps titf1-A, anticorps Xnkx-2.1, anticorps NKX2-1, anticorps LOC100227803, anticorps AV026640, anticorps Nkx2.1, anticorps T/EBP, anticorps Titf1, anticorps Ttf-1, anticorps nk2.1a, anticorps nkx2.1, anticorps nkx2.4a, anticorps titf1, anticorps titf1a, anticorps NK2 homeobox 1, anticorps NK2 homeobox 1 L homeolog, anticorps NK2 homeobox 4b, anticorps NKX2-1, anticorps nkx2-1.L, anticorps Nkx2-1, anticorps nkx2.4b
    Poids moléculaire
    40kDa
    ID gène
    7080
    UniProt
    P43699
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
Vous êtes ici:
Support technique