TTR anticorps
Aperçu rapide pour TTR anticorps (ABIN6940816)
Antigène
Voir toutes TTR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Transthyretin (Prealbumin) Antibody
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Specificité
- Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human full-length protein
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Isotype
- IgG2a, kappa
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Indications d'application
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Positive Control: HepG2, Pancreas and liver.
Known Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- TTR (Transthyretin (TTR))
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Autre désignation
- TTR
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Sujet
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Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody
HepG2 cell lysate or human kidney or Liver tissue lysate (WB).
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Poids moléculaire
- 15kDa
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ID gène
- 7276, 427202
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UniProt
- P02766
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Pathways
- Hormone Transport
Antigène
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