VLDLR anticorps (C-Term)

N° du produit ABIN6940886

L’anticorps Souris Monoclonal anti-VLDLR a été validé pour IHC, ISt et StM. Il convient pour détecter VLDLR dans des échantillons de Humain et Rat.

Aperçu rapide pour VLDLR anticorps (C-Term) (ABIN6940886)

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VLDLR est non-conjugé

Application: Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)

Clone: VLDLR-1337

Détail du produit anti-VLDLR anticorps

Épitope: C-Term

Purification: Purified by Protein A/G

Immunogène: Recombinant human VLDLR fragment from c-terminal

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur VLDLR

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDLR

Sujet: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Poids moléculaire: 143-161kDa

ID gène: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin