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PDCD1LG2 anticorps (AA 27-220)

PDCD1LG2 Reactivité: Humain WB, ELISA, FACS, IF, Coat Hôte: Souris Monoclonal PDL2-2676 unconjugated
N° du produit ABIN6940946
  • Antigène Voir toutes PDCD1LG2 Anticorps
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-220
    Reactivité
    • 76
    • 28
    • 10
    • 3
    Humain
    Hôte
    • 49
    • 31
    • 14
    • 1
    Souris
    Clonalité
    • 47
    • 45
    • 1
    Monoclonal
    Conjugué
    • 52
    • 10
    • 9
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDCD1LG2 est non-conjugé
    Application
    • 51
    • 44
    • 37
    • 30
    • 17
    • 11
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)
    Specificité
    Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
    Clone
    PDL2-2676
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PDCD1LG2 Anticorps primaire
  • Indications d'application

    Positive Control: Jurakt, HepG2, THP-1, RAW, NIH3T3, U87 cells Placenta or Pancreas. Thyroid Carcinoma.

    Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL),Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Autre désignation
    PDCD1LG2 (PDCD1LG2 Produits)
    Synonymes
    anticorps PDL2, anticorps B7DC, anticorps Btdc, anticorps CD273, anticorps PD-L2, anticorps PDCD1L2, anticorps bA574F11.2, anticorps B7-DC, anticorps F730015O22Rik, anticorps programmed cell death 1 ligand 2, anticorps PDCD1LG2, anticorps Pdcd1lg2
    Poids moléculaire
    31kDa
    ID gène
    80380
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