CD2 anticorps

N° du produit ABIN6941011

L’anticorps Souris Monoclonal anti-CD2 a été validé pour FACS, IF, WB et Func. Il convient pour détecter CD2 dans des échantillons de Humain.

Aperçu rapide pour CD2 anticorps (ABIN6941011)

Antigène: CD2

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Clone: 1E7E8-G4

Détail du produit anti-CD2 anticorps

Purification: Purified by Protein A/G

Immunogène: Human Thymocytes/Sezary T cells

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: MOLT-4, 293T or Jurkat cells. Lymph node and tonsil.

Known Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Poids moléculaire: 50kDa

ID gène: 914

UniProt: P06729