CD2 anticorps
Aperçu rapide pour CD2 anticorps (ABIN6941016)
Antigène
Voir toutes CD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified by Protein A/G
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Immunogène
- Recombinant human LFA2 protein
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Isotype
- IgG1 kappa
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Indications d'application
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Positive Control: MOLT-4, 293T or Jurkat cells. Lymph node and tonsil.
Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- CD2
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Autre désignation
- CD2
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Sujet
- CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
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Poids moléculaire
- 50kDa
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ID gène
- 914
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UniProt
- P06729
Antigène
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