CD7 anticorps

N° du produit ABIN6941068

Cet anticorps anti-CD7 Monoclonal Souris (Clone C7-511) (ABIN6941068) détecte spécifiquement CD7 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD7 anticorps (ABIN6941068)

Antigène: CD7

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD7 est non-conjugé

Application: ELISA

Clone: C7-511

Détail du produit anti-CD7 anticorps

Fonction: CD7 (T-Cell Leukemia Marker) Antibody

Specificité: Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length CD7 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Positive Control: Jurkat, HUT-78, Molt-4, CEM cells or human peripheral blood lymphocytes. Lymph node and tonsil.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD7

Antigène: CD7

Autre désignation: CD7

Sujet:

GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41

CEM cells or human peripheral blood lymphocytes. Lymph node and tonsil., HUT-78, Jurkat, Molt-4

Poids moléculaire: 40kDa

ID gène: 924, 186820

UniProt: P09564

Pathways: Cell-Cell Junction Organization