Recombinant CD27 anticorps

N° du produit ABIN6941126

Cet anticorps Lapin Monoclonal détecte spécifiquement CD27 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD27 anticorps (ABIN6941126)

Antigène: CD27 (CD27 Molecule (CD27))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD27 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: LPFS2-2034R

Détail du produit anti-CD27 anticorps

Fonction: Recombinant CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody

Specificité: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length CD22 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application:

Positive Control: Human peripheral blood lymphocytes. Human tonsil and lymph node.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD27

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: CD27

Sujet:

LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

Human peripheral blood lymphocytes. Human tonsil and lymph node.

Poids moléculaire: 120kDa

ID gène: 939, 355307

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints